The Réjuve medical device rapidly increases fiber bonds in the tissue matrix to provide a mechanically stronger long-lasting tear-resistant tissue. Thus, it could become a replacement or adjunct to common surgical procedures such as discectomies, spinal fusions, and spinal implants.

Réjuve is an injectable crosslinking device that mechanically strengthens and rapidly stabilizes the disc; thereby, reducing the pain of the patient. This micro-invasive procedure can be performed on an outpatient basis and should be complete with just one injection treatment. 

Introducing Réjuve- Your Spine Rejuvenated


The Réjuve medical device is designed to be effective in treating large avascular (no direct blood supply) load-supporting tissues like the spinal disc.


A key to Réjuve's effectiveness is the device's ability to promote crosslinking of fibrous proteins including collagen, which rejuvenates the spinal disk area.

Disc degeneration is happening to all of us; for most of us it causes pain!

  • Annulus tissue becomes delaminated, fissured, or micro-damaged; causing pain

  • Spinal joint becomes unstable; causing pain

  • Disc bulges against nerves; causing pain


Réjuve medical device reduces pain by:

  • Strengthening annulus against tearing and delamination

  • Increasing joint stability

  • Reducing disc bulge

Réjuve: Effectively Protected

There are twenty-five (25) issued patents to date with additional under review. Réjuve is also supported by thirty-two (32) peer-reviewed papers.

Intralink-Spine, Inc. has received ISO 13485:2016 certification for its Quality Management System (QMS) following review by its notified body, MedCert GmbH. ISO 13485:2016 is an internationally recognized quality standard specific to the medical device industry and signifies Intralink-Spine’s commitment to the highest level of medical device quality controls and meeting customer and international regulatory expectations.  

© 2018 by Intralink-Spine Inc.  Réjuveis a registered trademark of Intralink-Spine, Inc.

Attention: Réjuve™ is not available for sale in the US, Canada, or EU. Clinical studies are pending.